Chinese American Chromatography Association(CACA) Webinar
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Date: Aug 25th, 2021 12:00 PM EDT
Title: Application of ion chromatography in pharmaceutical industry
Speaker:
Yichen Wang, Specialist of Ion Chromatography, Product Manager of SHINE Ion Chromatography
Registration Link:
https://register.gotowebinar.com/register/7955049475103076098
Abstract:
Ion chromatography (IC), a well-established form of liquid chromatography, uses ion-exchange resins to separate cations or anions. There are two types of IC, anion-exchange and cation-exchange. Equipped with different detectors, IC could be a powerful separation technique to address challenging analytical tasks. For example, IC can detect carbohydrate in dairy products using electrochemical detector. Recently, IC has been extensively used for purification and characterization of biopharmaceutical drugs such as monoclonal antibody (mAb) and adeno-associated virus (AAV). Trace analysis of elemental impurities with low detection limit can be achieved with combination of ICP-MS/MS. It is possible to detect hexavalent ions such as chromium at ppt levels in toys.
Due to its excellent sensitivity, selectivity, and fast speed, IC has proven to be a very useful technique for determination of both organic and inorganic ions (in particular non-metal ions) and applied in various fields such as food, environmental, material and pharmaceutical analyses. To explore the growing interest of IC in pharmaceutical industry, this seminar will start with a brief introduction of IC principle, operation, and instrumentation followed by its application in analysis of raw materials, intermediates, drug substance, excipients, and finished drug products based on pharmacopeia standards from different countries.
Chinese American Chromatography Association
CACA was established in 2008 and has over 1000 members. CACA provides career development and networking opportunities at Pittcon, HPLC and other meetings, and CACA awards for young scientists and students at Pittcon. CACA has CACA technical sessions on separation sciences at iCC, EAS, CPSA etc. CACA organized webinars for sponsors (~20 webinars in the last three years). CACA uses communication platforms in LinkedIn, WeChat as well as the CACA Website.
While CACA members are mainly Chinese Americans and Chinese scientists working in the North America, all separation scientists of other nationalities and from other countries are welcome to join. The membership is on a voluntary basis and free of charge.